A variant NS1 protein from H5N2 avian influenza virus suppresses PKR activation and promotes replication and virulence in mammals

Highly pathogenic avian influenza viruses (HPAIVs) frequently receive global attention as threats to public health. The NS1 protein is a key virulence factor known to impair host antiviral responses. The study herein revealed HPAIV H5N2 NS gene encoded additional protein; a truncated NS1 variant, de...

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Detalles Bibliográficos
Autores principales: Chung, Yun-Ting, Kuan, Chih-Ying, Liao, Guan-Ru, Albrecht, Randy A., Tseng, Yeu-Yang, Hsu, Yu-Chen, Ou, Shan-Chia, Hsu, Wei-Li
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Taylor & Francis 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9559317/
https://www.ncbi.nlm.nih.gov/pubmed/35979918
http://dx.doi.org/10.1080/22221751.2022.2114853