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A variant NS1 protein from H5N2 avian influenza virus suppresses PKR activation and promotes replication and virulence in mammals
Highly pathogenic avian influenza viruses (HPAIVs) frequently receive global attention as threats to public health. The NS1 protein is a key virulence factor known to impair host antiviral responses. The study herein revealed HPAIV H5N2 NS gene encoded additional protein; a truncated NS1 variant, de...
Autores principales: | Chung, Yun-Ting, Kuan, Chih-Ying, Liao, Guan-Ru, Albrecht, Randy A., Tseng, Yeu-Yang, Hsu, Yu-Chen, Ou, Shan-Chia, Hsu, Wei-Li |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Taylor & Francis
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9559317/ https://www.ncbi.nlm.nih.gov/pubmed/35979918 http://dx.doi.org/10.1080/22221751.2022.2114853 |
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