Synergistic Effects of Sanglifehrin-Based Cyclophilin Inhibitor NV651 with Cisplatin in Hepatocellular Carcinoma

SIMPLE SUMMARY: Cyclophilins, one of the three families of proteins with peptidyl-prolyl isomerase activity, are overexpressed in several cancers, including hepatocellular carcinoma (HCC), and this overexpression is correlated with poor prognosis. Cyclophilins play an important role in cancer progre...

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Detalles Bibliográficos
Autores principales: Simón Serrano, Sonia, Tavecchio, Michele, Mallik, Josef, Grönberg, Alvar, Elmér, Eskil, Kifagi, Chamseddine, Gallay, Philippe, Hansson, Magnus Joakim, Massoumi, Ramin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9559492/
https://www.ncbi.nlm.nih.gov/pubmed/36230472
http://dx.doi.org/10.3390/cancers14194553

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