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Analysis of chromatin data supports a role for CD14+ monocytes/macrophages in mediating genetic risk for juvenile idiopathic arthritis

INTRODUCTION: Genome wide association studies (GWAS) have identified multiple regions that confer genetic risk for the polyarticular/oligoarticular forms of juvenile idiopathic arthritis (JIA). However, genome-wide scans do not identify the cells impacted by genetic polymorphisms on the risk haploty...

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Detalles Bibliográficos
Autores principales:	Crinzi, Elizabeth A., Haley, Emma K., Poppenberg, Kerry E., Jiang, Kaiyu, Tutino, Vincent M., Jarvis, James N.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Frontiers Media S.A. 2022
Materias:	Immunology
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9559786/ https://www.ncbi.nlm.nih.gov/pubmed/36248892 http://dx.doi.org/10.3389/fimmu.2022.913555

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