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Smad3 regulates smooth muscle cell fate and mediates adverse remodeling and calcification of the atherosclerotic plaque

Atherosclerotic plaques consist mostly of smooth muscle cells (SMC), and genes that influence SMC phenotype can modulate coronary artery disease (CAD) risk. Allelic variation at 15q22.33 has been identified by genome-wide association studies to modify the risk of CAD and is associated with the expre...

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Detalles Bibliográficos
Autores principales:	Cheng, Paul, Wirka, Robert C., Kim, Juyong Brian, Kim, Hyun-Jung, Nguyen, Trieu, Kundu, Ramendra, Zhao, Quanyi, Sharma, Disha, Pedroza, Albert, Nagao, Manabu, Iyer, Dharini, Fischbein, Michael P., Quertermous, Thomas
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	2022
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9560061/ https://www.ncbi.nlm.nih.gov/pubmed/36246779 http://dx.doi.org/10.1038/s44161-022-00042-8

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