Bronchus-associated macrophages efficiently capture and present soluble inhaled antigens and are capable of local Th2 cell activation

In allergic asthma, allergen inhalation leads to local Th2 cell activation and peribronchial inflammation. However, the mechanisms for local antigen capture and presentation remain unclear. By two-photon microscopy of the mouse lung, we established that soluble antigens in the bronchial airway lumen...

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Detalles Bibliográficos
Autores principales: Tang, Xin-Zi, Kreuk, Lieselotte S M, Cho, Cynthia, Metzger, Ross J, Allen, Christopher D C
Formato: Online Artículo Texto
Lenguaje:English
Publicado: eLife Sciences Publications, Ltd 2022
Materias:
Immunology and Inflammation
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9560158/
https://www.ncbi.nlm.nih.gov/pubmed/36173678
http://dx.doi.org/10.7554/eLife.63296

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9560158/
https://www.ncbi.nlm.nih.gov/pubmed/36173678
http://dx.doi.org/10.7554/eLife.63296

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