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Empirical single-cell tracking and cell-fate simulation reveal dual roles of p53 in tumor suppression

The tumor suppressor p53 regulates various stress responses via increasing its cellular levels. The lowest p53 levels occur in unstressed cells; however, the functions of these low levels remain unclear. To investigate the functions, we used empirical single-cell tracking of p53-expressing (Control)...

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Detalles Bibliográficos
Autores principales: Rancourt, Ann, Sato, Sachiko, Satoh, Masahiko S
Formato: Online Artículo Texto
Lenguaje:English
Publicado: eLife Sciences Publications, Ltd 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9560164/
https://www.ncbi.nlm.nih.gov/pubmed/36125118
http://dx.doi.org/10.7554/eLife.72498

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