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mPPases create a conserved anionic membrane fingerprint as identified via multi-scale simulations

Membrane-integral pyrophosphatases (mPPases) are membrane-bound enzymes responsible for hydrolysing inorganic pyrophosphate and translocating a cation across the membrane. Their function is essential for the infectivity of clinically relevant protozoan parasites and plant maturation. Recent developm...

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Detalles Bibliográficos
Autores principales: Holmes, Alexandra O. M., Goldman, Adrian, Kalli, Antreas C.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9560603/
https://www.ncbi.nlm.nih.gov/pubmed/36191052
http://dx.doi.org/10.1371/journal.pcbi.1010578

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