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mPPases create a conserved anionic membrane fingerprint as identified via multi-scale simulations
Membrane-integral pyrophosphatases (mPPases) are membrane-bound enzymes responsible for hydrolysing inorganic pyrophosphate and translocating a cation across the membrane. Their function is essential for the infectivity of clinically relevant protozoan parasites and plant maturation. Recent developm...
Autores principales: | Holmes, Alexandra O. M., Goldman, Adrian, Kalli, Antreas C. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9560603/ https://www.ncbi.nlm.nih.gov/pubmed/36191052 http://dx.doi.org/10.1371/journal.pcbi.1010578 |
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