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A pals-25 gain-of-function allele triggers systemic resistance against natural pathogens of C. elegans

Regulation of immunity throughout an organism is critical for host defense. Previous studies in the nematode Caenorhabditis elegans have described an “ON/OFF” immune switch comprised of the antagonistic paralogs PALS-25 and PALS-22, which regulate resistance against intestinal and epidermal pathogen...

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Detalles Bibliográficos
Autores principales:	Gang, Spencer S., Grover, Manish, Reddy, Kirthi C., Raman, Deevya, Chang, Ya-Ting, Ekiert, Damian C., Barkoulas, Michalis, Troemel, Emily R.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Public Library of Science 2022
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9560605/ https://www.ncbi.nlm.nih.gov/pubmed/36191002 http://dx.doi.org/10.1371/journal.pgen.1010314

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