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Analysis of low-level somatic mosaicism reveals stage and tissue-specific mutational features in human development

Most somatic mutations that arise during normal development are present at low levels in single or multiple tissues depending on the developmental stage and affected organs. However, the effect of human developmental stages or mutations of different organs on the features of somatic mutations is sti...

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Detalles Bibliográficos
Autores principales: Kim, Ja Hye, Hwang, Shinwon, Son, Hyeonju, Kim, Dongsun, Kim, Il Bin, Kim, Myeong-Heui, Sim, Nam Suk, Kim, Dong Seok, Ha, Yoo-Jin, Lee, Junehawk, Kang, Hoon-Chul, Lee, Jeong Ho, Kim, Sangwoo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9560606/
https://www.ncbi.nlm.nih.gov/pubmed/36121845
http://dx.doi.org/10.1371/journal.pgen.1010404