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The expression of metalloproteinases in the lumbar disc correlates strongly with Pfirrmann MRI grades in lumbar spinal fusion patients

INTRODUCTION: Increased catabolism of the extracellular matrix is observed under degenerative disc disease (DDD). The cleavage of extracellular matrix proteins in the nucleus pulposus (NP) by either matrix metalloproteinases (MMPs) or a disintegrin and metalloproteinases with thrombospondin motifs (...

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Detalles Bibliográficos
Autores principales:	Aripaka, Sanjay S., Bech-Azeddine, Rachid, Jørgensen, Louise M., Mikkelsen, Jens D.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Elsevier 2022
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9560696/ https://www.ncbi.nlm.nih.gov/pubmed/36248158 http://dx.doi.org/10.1016/j.bas.2022.100872

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