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LncRNA-PAX8-AS1 Silencing Decreases Cell Viability, Enhances Apoptosis, and Suppresses Doxorubicin Resistance in Myeloid Leukemia via the miR-378g/ERBB2 Axis

OBJECTIVE: Considering the role of lncRNAs reported as regulators in acute myeloid leukemia (AML) progression, the current research aims to investigate the role of PAX8-AS1 in chemo-resistant AML. METHODS: Human AML cells HL60 and human doxorubicin (ADM)-resistant AML cells (HL60/ADM cells) were use...

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Detalles Bibliográficos
Autores principales:	Song, Xiaolu, Chen, Yirui, Peng, Ye, Wang, Xiaogang, Zheng, Sujie, Shi, Fangfang, Lan, Jianping
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Hindawi 2022
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9560823/ https://www.ncbi.nlm.nih.gov/pubmed/36248434 http://dx.doi.org/10.1155/2022/2295044

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