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Hijacking the self-replicating machine of bacteriophage for PCR-based cascade signal amplification in detecting SARS-CoV-2 viral marker protein in serum

In this work, the nucleic acid detection of SARS-Cov-2 is extended to protein markers of the virus, utilizing bacteriophage. Specifically, the phage display technique enables the main protease of SARS-Cov-2 to control the self-replication of m13 phage, so that the presence of the viral protease can...

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Detalles Bibliográficos
Autores principales: Du, Jialei, Xiang, Daili, Liu, Fushan, Wang, Leichen, Li, Hao, Gong, Liu, Fan, Xiangyu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier B.V. 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9560943/
https://www.ncbi.nlm.nih.gov/pubmed/36267643
http://dx.doi.org/10.1016/j.snb.2022.132780