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Network Analysis for Signal Detection in Spontaneous Adverse Event Reporting Database: Application of Network Weighting Normalization to Characterize Cardiovascular Drug Safety

INTRODUCTION: Signal detection yields confirmed signals in only 2.1%, which imposes a heavy burden on the pharmacovigilance system in the European Union. OBJECTIVES: We aimed to develop a network theoretical metric to increase the confirmed signal ratio of individual case safety report (ICSR) networ...

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Detalles Bibliográficos
Autores principales:	Pétervári, Mátyás, Benczik, Bettina, Balogh, Olivér M., Petrovich, Balázs, Ágg, Bence, Ferdinandy, Péter
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Springer International Publishing 2022
Materias:	Original Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9561003/ https://www.ncbi.nlm.nih.gov/pubmed/36198930 http://dx.doi.org/10.1007/s40264-022-01225-9

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