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Pax3 loss of function delays tumour progression in kRAS-induced zebrafish rhabdomyosarcoma models

Rhabdomyosarcoma is a soft tissue cancer that arises in skeletal muscle due to mutations in myogenic progenitors that lead to ineffective differentiation and malignant transformation. The transcription factors Pax3 and Pax7 and their downstream target genes are tightly linked with the fusion positiv...

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Detalles Bibliográficos
Autores principales:	Kahsay, A., Rodriguez-Marquez, E., López-Pérez, A., Hörnblad, A., von Hofsten, J.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group UK 2022
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9561152/ https://www.ncbi.nlm.nih.gov/pubmed/36229514 http://dx.doi.org/10.1038/s41598-022-21525-5

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