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Inhibition of Mps1 kinase enhances taxanes efficacy in castration resistant prostate cancer
Androgen ablation therapy is the standard of care for newly diagnosed prostate cancer (PC) patients. PC that relapsed after hormonal therapy, referred to as castration-resistant PC (CRPC), often presents with metastasis (mCRPC) and is the major cause of disease lethality. The few available therapies...
Autores principales: | Sarwar, Sadia, Morozov, Viacheslav M., Purayil, Hamsa, Daaka, Yehia, Ishov, Alexander M. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9561175/ https://www.ncbi.nlm.nih.gov/pubmed/36229449 http://dx.doi.org/10.1038/s41419-022-05312-8 |
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