Brown Tumors Belong to the Spectrum of KRAS-driven Neoplasms

Brown tumors are rare and generally self-limiting mass lesions of bone occurring in the context of hyperparathyroidism. Although commonly regarded as endocrine-driven tumor-like lesions, we detected pathogenic hotspot KRAS mutations in 10/16 brown tumors (62%) with similar frequencies found in cases...

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Detalles Bibliográficos
Autores principales: Turek, Daniel, Haefliger, Simon, Ameline, Baptiste, Alborelli, Ilaria, Calgua, Byron, Hartmann, Wolfgang, Harder, Dorothee, Flanagan, Adrienne M., Amary, Fernanda, Baumhoer, Daniel
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Lippincott Williams & Wilkins 2022
Materias:
Original Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9561227/
https://www.ncbi.nlm.nih.gov/pubmed/36040039
http://dx.doi.org/10.1097/PAS.0000000000001963

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