Cargando…
Preclinical studies of NOS inhibitor T1059 vasopressor activity on the models of acute hemorrhagic shock in rats and dogs
The development of new effective and safe vasopressors is one of the ways to increase the effectiveness of the treatment of hypotensive disorders, the severe forms of which remain a common cause of death in all countries of the world. Previously, we synthesized the original compound T1059, a selecti...
Autores principales: | Filimonova, Marina, Shevchenko, Ljudmila, Makarchuk, Victoria, Saburova, Alina, Shegay, Petr, Kaprin, Andrey, Ivanov, Sergey, Filimonov, Alexander |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2022
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9561252/ https://www.ncbi.nlm.nih.gov/pubmed/36249787 http://dx.doi.org/10.3389/fphar.2022.995272 |
Ejemplares similares
-
Combination of NOS- and PDK-Inhibitory Activity: Possible Way to Enhance Antitumor Effects
por: Filimonova, Marina, et al.
Publicado: (2022) -
The Ability of the Nitric Oxide Synthases Inhibitor T1023 to Selectively Protect the Non-Malignant Tissues
por: Filimonova, Marina, et al.
Publicado: (2021) -
1-Isobutanoil-2-isopropylisothiourea Phosphate, T1082: A Safe and Effective Prevention of Radiotherapy Complications in Oncology
por: Filimonova, Marina, et al.
Publicado: (2022) -
Evaluation of In Vitro Cytotoxic Potential of Avarol towards Human Cancer Cell Lines and In Vivo Antitumor Activity in Solid Tumor Models
por: Stanojkovic, Tatjana P., et al.
Publicado: (2022) -
Does vasopressor therapy have an indication in hemorrhagic shock?
por: Beloncle, François, et al.
Publicado: (2013)