The transcriptional coactivator Eya1 exerts transcriptional repressive activity by interacting with REST corepressors and REST-binding sequences to maintain nephron progenitor identity

Eya1 is critical for establishing and maintaining nephron progenitor cells (NPCs). It belongs to a family of proteins called phosphatase-transcriptional activators but without intrinsic DNA-binding activity. However, the spectrum of the Eya1-centered networks is underexplored. Here, we combined tran...

Descripción completa

Detalles Bibliográficos
Autores principales: Li, Jun, Cheng, Chunming, Xu, Jinshu, Zhang, Ting, Tokat, Bengu, Dolios, Georgia, Ramakrishnan, Aarthi, Shen, Li, Wang, Rong, Xu, Pin-Xian
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2022
Materias:
Gene regulation, Chromatin and Epigenetics
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9561260/
https://www.ncbi.nlm.nih.gov/pubmed/36130284
http://dx.doi.org/10.1093/nar/gkac760

Ejemplares similares

Ejemplares similares