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Whole-genome long-read TAPS deciphers DNA methylation patterns at base resolution using PacBio SMRT sequencing technology

Long-read sequencing provides valuable information on difficult-to-map genomic regions, which can complement short-read sequencing to improve genome assembly, yet limited methods are available to accurately detect DNA methylation over long distances at a whole-genome scale. By combining our recently...

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Detalles Bibliográficos
Autores principales: Chen, Jinfeng, Cheng, Jingfei, Chen, Xiufei, Inoue, Masato, Liu, Yibin, Song, Chun-Xiao
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9561279/
https://www.ncbi.nlm.nih.gov/pubmed/35849350
http://dx.doi.org/10.1093/nar/gkac612