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DDX17 is required for efficient DSB repair at DNA:RNA hybrid deficient loci

Proteins with RNA-binding activity are increasingly being implicated in DNA damage responses (DDR). Additionally, DNA:RNA-hybrids are rapidly generated around DNA double-strand breaks (DSBs), and are essential for effective repair. Here, using a meta-analysis of proteomic data, we identify novel DNA...

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Detalles Bibliográficos
Autores principales:	Bader, Aldo S, Luessing, Janna, Hawley, Ben R, Skalka, George L, Lu, Wei-Ting, Lowndes, Noel F, Bushell, Martin
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Oxford University Press 2022
Materias:	Genome Integrity, Repair and Replication
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9561282/ https://www.ncbi.nlm.nih.gov/pubmed/36200807 http://dx.doi.org/10.1093/nar/gkac843

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