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Human NOP2/NSUN1 regulates ribosome biogenesis through non-catalytic complex formation with box C/D snoRNPs
5-Methylcytosine (m(5)C) is a base modification broadly found on various RNAs in the human transcriptome. In eukaryotes, m(5)C is catalyzed by enzymes of the NSUN family composed of seven human members (NSUN1-7). NOP2/NSUN1 has been primarily characterized in budding yeast as an essential ribosome b...
Autores principales: | , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Oxford University Press
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9561284/ https://www.ncbi.nlm.nih.gov/pubmed/36161484 http://dx.doi.org/10.1093/nar/gkac817 |