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Human NOP2/NSUN1 regulates ribosome biogenesis through non-catalytic complex formation with box C/D snoRNPs

5-Methylcytosine (m(5)C) is a base modification broadly found on various RNAs in the human transcriptome. In eukaryotes, m(5)C is catalyzed by enzymes of the NSUN family composed of seven human members (NSUN1-7). NOP2/NSUN1 has been primarily characterized in budding yeast as an essential ribosome b...

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Detalles Bibliográficos
Autores principales: Liao, Han, Gaur, Anushri, McConie, Hunter, Shekar, Amirtha, Wang, Karen, Chang, Jeffrey T, Breton, Ghislain, Denicourt, Catherine
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9561284/
https://www.ncbi.nlm.nih.gov/pubmed/36161484
http://dx.doi.org/10.1093/nar/gkac817