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Uncovering translation roadblocks during the development of a synthetic tRNA

Ribosomes are remarkable in their malleability to accept diverse aminoacyl-tRNA substrates from both the same organism and other organisms or domains of life. This is a critical feature of the ribosome that allows the use of orthogonal translation systems for genetic code expansion. Optimization of...

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Detalles Bibliográficos
Autores principales: Prabhakar, Arjun, Krahn, Natalie, Zhang, Jingji, Vargas-Rodriguez, Oscar, Krupkin, Miri, Fu, Ziao, Acosta-Reyes, Francisco J, Ge, Xueliang, Choi, Junhong, Crnković, Ana, Ehrenberg, Måns, Puglisi, Elisabetta Viani, Söll, Dieter, Puglisi, Joseph
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9561287/
https://www.ncbi.nlm.nih.gov/pubmed/35882385
http://dx.doi.org/10.1093/nar/gkac576