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Human RNase 4 improves mRNA sequence characterization by LC–MS/MS

With the rapid growth of synthetic messenger RNA (mRNA)-based therapeutics and vaccines, the development of analytical tools for characterization of long, complex RNAs has become essential. Tandem liquid chromatography–mass spectrometry (LC–MS/MS) permits direct assessment of the mRNA primary sequen...

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Detalles Bibliográficos
Autores principales: Wolf, Eric J, Grünberg, Sebastian, Dai, Nan, Chen, Tien-Hao, Roy, Bijoyita, Yigit, Erbay, Corrêa, Ivan R
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9561288/
https://www.ncbi.nlm.nih.gov/pubmed/35871301
http://dx.doi.org/10.1093/nar/gkac632