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Selective human factor VIII activity measurement after analytical in‐line purification

BACKGROUND: It is essential to measure the activity of factor VIII (FVIII) throughout the life cycle of a coagulation FVIII concentrate. Such measurement in nonclinical pharmacokinetic studies is potentially biased by the presence of endogenous nonhuman FVIII, and certain manufacturing process–relat...

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Detalles Bibliográficos
Autores principales:	Engelmaier, Andrea, Schrenk, Gerald, Billwein, Manfred, Gritsch, Herbert, Zlabinger, Christoph, Weber, Alfred
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	John Wiley and Sons Inc. 2022
Materias:	Methodological Articles
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9561358/ https://www.ncbi.nlm.nih.gov/pubmed/36254254 http://dx.doi.org/10.1002/rth2.12821

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