Reversal of Clinically Significant Portal Hypertension After Immunosuppressive Treatment in a Patient With Sarcoidosis

Sarcoidosis is a multisystemic disease which features non-necrotizing granulomas in lungs and other organs. Hepatic involvement in sarcoidosis varies between a mild asymptomatic disease and a progressive inflammatory granulomatous disease with or without cirrhosis. In this case presentation, we pres...

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Autores principales: Yardeni, David, Hercun, Julian, Rodriguez, Gracia Viana, Fontana, Joseph R., Kleiner, David E., Koh, Christopher, Heller, Theo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Wolters Kluwer 2022
Materias:
Case Report
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9561428/
https://www.ncbi.nlm.nih.gov/pubmed/36247383
http://dx.doi.org/10.14309/crj.0000000000000874
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author Yardeni, David
Hercun, Julian
Rodriguez, Gracia Viana
Fontana, Joseph R.
Kleiner, David E.
Koh, Christopher
Heller, Theo
author_facet Yardeni, David
Hercun, Julian
Rodriguez, Gracia Viana
Fontana, Joseph R.
Kleiner, David E.
Koh, Christopher
Heller, Theo
author_sort Yardeni, David
collection PubMed
description Sarcoidosis is a multisystemic disease which features non-necrotizing granulomas in lungs and other organs. Hepatic involvement in sarcoidosis varies between a mild asymptomatic disease and a progressive inflammatory granulomatous disease with or without cirrhosis. In this case presentation, we present a case of hepatic sarcoidosis complicated by clinically significant portal hypertension including splenomegaly and gastroesophageal varices successfully treated with immunosuppression to achieve portal hypertension reversal.
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spelling pubmed-95614282022-10-14 Reversal of Clinically Significant Portal Hypertension After Immunosuppressive Treatment in a Patient With Sarcoidosis Yardeni, David Hercun, Julian Rodriguez, Gracia Viana Fontana, Joseph R. Kleiner, David E. Koh, Christopher Heller, Theo ACG Case Rep J Case Report Sarcoidosis is a multisystemic disease which features non-necrotizing granulomas in lungs and other organs. Hepatic involvement in sarcoidosis varies between a mild asymptomatic disease and a progressive inflammatory granulomatous disease with or without cirrhosis. In this case presentation, we present a case of hepatic sarcoidosis complicated by clinically significant portal hypertension including splenomegaly and gastroesophageal varices successfully treated with immunosuppression to achieve portal hypertension reversal. Wolters Kluwer 2022-10-12 /pmc/articles/PMC9561428/ /pubmed/36247383 http://dx.doi.org/10.14309/crj.0000000000000874 Text en Written work prepared by employees of the Federal Government as part of their official duties is, under the U.S. Copyright Act, a “work of the United States Government” for which copyright protection under Title 17 of the United States Code is not available. As such, copyright does not extend to the contributions of employees of the Federal Government. https://creativecommons.org/licenses/by-nc-nd/4.0/This is an open access article distributed under the terms of the Creative Commons Attribution-Non Commercial-No Derivatives License 4.0 (CCBY-NC-ND) (https://creativecommons.org/licenses/by-nc-nd/4.0/) , where it is permissible to download and share the work provided it is properly cited. The work cannot be changed in any way or used commercially without permission from the journal.
spellingShingle Case Report
Yardeni, David
Hercun, Julian
Rodriguez, Gracia Viana
Fontana, Joseph R.
Kleiner, David E.
Koh, Christopher
Heller, Theo
Reversal of Clinically Significant Portal Hypertension After Immunosuppressive Treatment in a Patient With Sarcoidosis
title Reversal of Clinically Significant Portal Hypertension After Immunosuppressive Treatment in a Patient With Sarcoidosis
title_full Reversal of Clinically Significant Portal Hypertension After Immunosuppressive Treatment in a Patient With Sarcoidosis
title_fullStr Reversal of Clinically Significant Portal Hypertension After Immunosuppressive Treatment in a Patient With Sarcoidosis
title_full_unstemmed Reversal of Clinically Significant Portal Hypertension After Immunosuppressive Treatment in a Patient With Sarcoidosis
title_short Reversal of Clinically Significant Portal Hypertension After Immunosuppressive Treatment in a Patient With Sarcoidosis
title_sort reversal of clinically significant portal hypertension after immunosuppressive treatment in a patient with sarcoidosis
topic Case Report
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9561428/
https://www.ncbi.nlm.nih.gov/pubmed/36247383
http://dx.doi.org/10.14309/crj.0000000000000874
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