Cargando…

Herbal tea, a novel adjuvant therapy for treating type 2 diabetes mellitus: A review

Type 2 diabetes mellitus (T2DM) is a metabolic, endocrine disease characterized by persistent hyperglycemia. Several studies have shown that herbal tea improves glucose metabolism disorders in patients with T2DM. This study summarizes the published randomized controlled trials (RCTs) on herbal tea a...

Descripción completa

Detalles Bibliográficos
Autores principales: Zhang, Xiangyuan, Zhang, Lili, Zhang, Boxun, Liu, Ke, Sun, Jun, Li, Qingwei, Zhao, Linhua
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9561533/
https://www.ncbi.nlm.nih.gov/pubmed/36249806
http://dx.doi.org/10.3389/fphar.2022.982387
_version_ 1784807965906173952
author Zhang, Xiangyuan
Zhang, Lili
Zhang, Boxun
Liu, Ke
Sun, Jun
Li, Qingwei
Zhao, Linhua
author_facet Zhang, Xiangyuan
Zhang, Lili
Zhang, Boxun
Liu, Ke
Sun, Jun
Li, Qingwei
Zhao, Linhua
author_sort Zhang, Xiangyuan
collection PubMed
description Type 2 diabetes mellitus (T2DM) is a metabolic, endocrine disease characterized by persistent hyperglycemia. Several studies have shown that herbal tea improves glucose metabolism disorders in patients with T2DM. This study summarizes the published randomized controlled trials (RCTs) on herbal tea as a adjuvant therapy for treating T2DM and found that herbal teas have potential add-on effects in lowering blood glucose levels. In addition, we discussed the polyphenol contents in common herbal teas and their possible adverse effects. To better guide the application of herbal teas, we further summarized the hypoglycemic mechanisms of common herbal teas, which mainly involve: 1) improving insulin resistance, 2) protecting islet β-cells, 3) anti-inflammation and anti-oxidation, 4) inhibition of glucose absorption, and 5) suppression of gluconeogenesis. In conclusion, herbal tea, as a novel adjuvant therapy for treating T2DM, has the potential for further in-depth research and product development.
format Online
Article
Text
id pubmed-9561533
institution National Center for Biotechnology Information
language English
publishDate 2022
publisher Frontiers Media S.A.
record_format MEDLINE/PubMed
spelling pubmed-95615332022-10-15 Herbal tea, a novel adjuvant therapy for treating type 2 diabetes mellitus: A review Zhang, Xiangyuan Zhang, Lili Zhang, Boxun Liu, Ke Sun, Jun Li, Qingwei Zhao, Linhua Front Pharmacol Pharmacology Type 2 diabetes mellitus (T2DM) is a metabolic, endocrine disease characterized by persistent hyperglycemia. Several studies have shown that herbal tea improves glucose metabolism disorders in patients with T2DM. This study summarizes the published randomized controlled trials (RCTs) on herbal tea as a adjuvant therapy for treating T2DM and found that herbal teas have potential add-on effects in lowering blood glucose levels. In addition, we discussed the polyphenol contents in common herbal teas and their possible adverse effects. To better guide the application of herbal teas, we further summarized the hypoglycemic mechanisms of common herbal teas, which mainly involve: 1) improving insulin resistance, 2) protecting islet β-cells, 3) anti-inflammation and anti-oxidation, 4) inhibition of glucose absorption, and 5) suppression of gluconeogenesis. In conclusion, herbal tea, as a novel adjuvant therapy for treating T2DM, has the potential for further in-depth research and product development. Frontiers Media S.A. 2022-09-30 /pmc/articles/PMC9561533/ /pubmed/36249806 http://dx.doi.org/10.3389/fphar.2022.982387 Text en Copyright © 2022 Zhang, Zhang, Zhang, Liu, Sun, Li and Zhao. https://creativecommons.org/licenses/by/4.0/This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.
spellingShingle Pharmacology
Zhang, Xiangyuan
Zhang, Lili
Zhang, Boxun
Liu, Ke
Sun, Jun
Li, Qingwei
Zhao, Linhua
Herbal tea, a novel adjuvant therapy for treating type 2 diabetes mellitus: A review
title Herbal tea, a novel adjuvant therapy for treating type 2 diabetes mellitus: A review
title_full Herbal tea, a novel adjuvant therapy for treating type 2 diabetes mellitus: A review
title_fullStr Herbal tea, a novel adjuvant therapy for treating type 2 diabetes mellitus: A review
title_full_unstemmed Herbal tea, a novel adjuvant therapy for treating type 2 diabetes mellitus: A review
title_short Herbal tea, a novel adjuvant therapy for treating type 2 diabetes mellitus: A review
title_sort herbal tea, a novel adjuvant therapy for treating type 2 diabetes mellitus: a review
topic Pharmacology
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9561533/
https://www.ncbi.nlm.nih.gov/pubmed/36249806
http://dx.doi.org/10.3389/fphar.2022.982387
work_keys_str_mv AT zhangxiangyuan herbalteaanoveladjuvanttherapyfortreatingtype2diabetesmellitusareview
AT zhanglili herbalteaanoveladjuvanttherapyfortreatingtype2diabetesmellitusareview
AT zhangboxun herbalteaanoveladjuvanttherapyfortreatingtype2diabetesmellitusareview
AT liuke herbalteaanoveladjuvanttherapyfortreatingtype2diabetesmellitusareview
AT sunjun herbalteaanoveladjuvanttherapyfortreatingtype2diabetesmellitusareview
AT liqingwei herbalteaanoveladjuvanttherapyfortreatingtype2diabetesmellitusareview
AT zhaolinhua herbalteaanoveladjuvanttherapyfortreatingtype2diabetesmellitusareview