TGFβ superfamily signaling regulates the state of human stem cell pluripotency and capacity to create well-structured telencephalic organoids

Telencephalic organoids generated from human pluripotent stem cells (hPSCs) are a promising system for studying the distinct features of the developing human brain and the underlying causes of many neurological disorders. While organoid technology is steadily advancing, many challenges remain, inclu...

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Detalles Bibliográficos
Autores principales: Watanabe, Momoko, Buth, Jessie E., Haney, Jillian R., Vishlaghi, Neda, Turcios, Felix, Elahi, Lubayna S., Gu, Wen, Pearson, Caroline A., Kurdian, Arinnae, Baliaouri, Natella V., Collier, Amanda J., Miranda, Osvaldo A., Dunn, Natassia, Chen, Di, Sabri, Shan, Torre-Ubieta, Luis de la, Clark, Amander T., Plath, Kathrin, Christofk, Heather R., Kornblum, Harley I., Gandal, Michael J., Novitch, Bennett G.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9561534/
https://www.ncbi.nlm.nih.gov/pubmed/36179695
http://dx.doi.org/10.1016/j.stemcr.2022.08.013

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