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Effects of targeted-edited oncogenic insulin-like growth factor-1 receptor with specific-sgRNA on biological behaviors of HepG2 cells

BACKGROUND: Insulin-like growth factor-1 receptor (IGF-1R) is over-expressed in hepatocellular carcinoma (HCC). However, the relationship between IGF-1R activation and HCC progression remains unidentified. AIM: To investigate the effects of editing IGF-1R on the biological features of HCC cells. MET...

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Detalles Bibliográficos
Autores principales: Yao, Min, Cai, Yin, Wu, Zhi-Jun, Zhou, Ping, Sai, Wen-Li, Wang, De-Feng, Wang, Li, Yao, Deng-Fu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Baishideng Publishing Group Inc 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9561564/
https://www.ncbi.nlm.nih.gov/pubmed/36246809
http://dx.doi.org/10.12998/wjcc.v10.i28.10017