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PIM3-AMPK-HDAC4/5 axis restricts MuERVL-marked 2-cell-like state in embryonic stem cells

A minority of embryonic stem cells (ESCs) marked by endogenous retrovirus MuERVL are totipotent 2-cell-like cells. However, the majority of ESCs repress MuERVL. Currently, it is still unclear regarding the signaling pathway(s) repressing the MuERVL-associated 2-cell-like state of ESCs. Here, we iden...

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Detalles Bibliográficos
Autores principales:	Zhao, Xin, Shen, Jian, Zhao, Xuan, Zhang, Miao, Feng, Xiao, Zhang, Weiyu, Lu, Xinyi
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Elsevier 2022
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9561635/ https://www.ncbi.nlm.nih.gov/pubmed/36150380 http://dx.doi.org/10.1016/j.stemcr.2022.08.009

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