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Sporozoite motility as a quantitative readout for anti-CSP antibody inhibition

Antibodies can prevent malaria by neutralizing the infectious Plasmodium falciparum sporozoites (SPZ) before they establish an infection in the liver. Circumsporozoite protein (CSP), the most abundant surface protein of SPZ is the leading candidate for passive (and subunit) immunization approaches a...

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Detalles Bibliográficos
Autores principales: de Korne, C. M., van Schuijlenburg, R., Sijtsma, J. C., de Bes, H. M., Baalbergen, E., Azargoshasb, S., van Oosterom, M. N., McCall, M. B. B., van Leeuwen, F. W. B., Roestenberg, M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9561690/
https://www.ncbi.nlm.nih.gov/pubmed/36229488
http://dx.doi.org/10.1038/s41598-022-22154-8