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A predictive computational platform for optimizing the design of bioartificial pancreas devices

The delivery of encapsulated islets or stem cell-derived insulin-producing cells (i.e., bioartificial pancreas devices) may achieve a functional cure for type 1 diabetes, but their efficacy is limited by mass transport constraints. Modeling such constraints is thus desirable, but previous efforts in...

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Detalles Bibliográficos
Autores principales: Ernst, Alexander U., Wang, Long-Hai, Worland, Scott C., Marfil-Garza, Braulio A., Wang, Xi, Liu, Wanjun, Chiu, Alan, Kin, Tatsuya, O’Gorman, Doug, Steinschneider, Scott, Datta, Ashim K., Papas, Klearchos K., James Shapiro, A. M., Ma, Minglin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9561707/
https://www.ncbi.nlm.nih.gov/pubmed/36229614
http://dx.doi.org/10.1038/s41467-022-33760-5