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A predictive computational platform for optimizing the design of bioartificial pancreas devices
The delivery of encapsulated islets or stem cell-derived insulin-producing cells (i.e., bioartificial pancreas devices) may achieve a functional cure for type 1 diabetes, but their efficacy is limited by mass transport constraints. Modeling such constraints is thus desirable, but previous efforts in...
Autores principales: | Ernst, Alexander U., Wang, Long-Hai, Worland, Scott C., Marfil-Garza, Braulio A., Wang, Xi, Liu, Wanjun, Chiu, Alan, Kin, Tatsuya, O’Gorman, Doug, Steinschneider, Scott, Datta, Ashim K., Papas, Klearchos K., James Shapiro, A. M., Ma, Minglin |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9561707/ https://www.ncbi.nlm.nih.gov/pubmed/36229614 http://dx.doi.org/10.1038/s41467-022-33760-5 |
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