Antihypertension Nanoblockers Increase Intratumoral Perfusion of Sequential Cytotoxic Nanoparticles to Enhance Chemotherapy Efficacy against Pancreatic Cancer

Pancreatic ductal adenocarcinoma (PDAC), one of the worst prognosis types of tumors, is characterized by dense extracellular matrix, which compresses tumor vessels and forms a physical barrier to inhibit therapeutic drug penetration and efficacy. Herein, losartan, an antihypertension agent, is appli...

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Detalles Bibliográficos
Autores principales: Bian, Suchen, Dong, Haijiang, Zhao, Long, Li, Zequn, Chen, Jian, Zhu, Xingxin, Qiu, Nasha, Jia, Xing, Song, Wenfeng, Li, Zekuan, Zheng, Shusen, Wang, Hangxiang, Song, Penghong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2022
Materias:
Research Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9561769/
https://www.ncbi.nlm.nih.gov/pubmed/36026578
http://dx.doi.org/10.1002/advs.202201931

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