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Krüppel-Like Factor 1: A Pivotal Gene Regulator in Erythropoiesis

Krüppel-like factor 1 (KLF1) plays a crucial role in erythropoiesis. In-depth studies conducted on mice and humans have highlighted its importance in erythroid lineage commitment, terminal erythropoiesis progression and the switching of globin genes from γ to β. The role of KLF1 in haemoglobin switc...

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Detalles Bibliográficos
Autores principales: Caria, Cristian Antonio, Faà, Valeria, Ristaldi, Maria Serafina
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9561966/
https://www.ncbi.nlm.nih.gov/pubmed/36231031
http://dx.doi.org/10.3390/cells11193069

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