Cargando…

Prolonged Antiretroviral Treatment Induces Adipose Tissue Remodelling Associated with Mild Inflammation in SIV-Infected Macaques

During chronic SIV/HIV infection, adipose tissue (AT) is the target of both antiretroviral treatment (ART) and the virus. AT might subsequently contribute to the low-grade systemic inflammation observed in patients on ART. To evaluate the inflammatory profile of AT during chronic SIV/HIV infection,...

Descripción completa

Detalles Bibliográficos
Autores principales:	Mausoléo, Aude, Olivo, Anaelle, Desjardins, Delphine, Sáez-Cirión, Asier, Barrail-Tran, Aurélie, Avettand-Fenoel, Véronique, Noël, Nicolas, Lagathu, Claire, Béréziat, Véronique, Le Grand, Roger, Lambotte, Olivier, Bourgeois, Christine
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2022
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9561982/ https://www.ncbi.nlm.nih.gov/pubmed/36231066 http://dx.doi.org/10.3390/cells11193104

Ejemplares similares

Specific Biological Features of Adipose Tissue, and Their Impact on HIV Persistence
por: Bourgeois, Christine, et al.
Publicado: (2019)

Antiretroviral therapy for HIV controllers: Reasons for initiation and outcomes in the French ANRS-CO21 CODEX cohort
por: Plaçais, Léo, et al.
Publicado: (2021)

SIV Infection and the HIV Proteins Tat and Nef Induce Senescence in Adipose Tissue and Human Adipose Stem Cells, Resulting in Adipocyte Dysfunction
por: Gorwood, Jennifer, et al.
Publicado: (2020)

Expansion of Immature Neutrophils During SIV Infection Is Associated With Their Capacity to Modulate T-Cell Function
por: Lemaitre, Julien, et al.
Publicado: (2022)

Pharmacological Validation of Long-Term Treatment with Antiretroviral Drugs in a Model of SIV-Infected Non-Human Primates
por: Gelé, Thibaut, et al.
Publicado: (2022)

Contribution of Adipose Tissue to the Chronic Immune Activation and Inflammation Associated With HIV Infection and Its Treatment
por: Bourgeois, Christine, et al.
Publicado: (2021)

Inhibition of Adipose Tissue Beiging by HIV Integrase Inhibitors, Dolutegravir and Bictegravir, Is Associated with Adipocyte Hypertrophy, Hypoxia, Elevated Fibrosis, and Insulin Resistance in Simian Adipose Tissue and Human Adipocytes
por: Ngono Ayissi, Kenza, et al.
Publicado: (2022)

Immunologic and Virologic Progression in HIV Controllers: The Role of Viral “Blips” and Immune Activation in the ANRS CO21 CODEX Study
por: Noel, Nicolas, et al.
Publicado: (2015)

A Subset of Extreme Human Immunodeficiency Virus (HIV) Controllers Is Characterized by a Small HIV Blood Reservoir and a Weak T-Cell Activation Level
por: Canouï, Etienne, et al.
Publicado: (2017)

CD4 Dynamics over a 15 Year-Period among HIV Controllers Enrolled in the ANRS French Observatory
por: Boufassa, Faroudy, et al.
Publicado: (2011)

Cynomolgus macaque IL37 polymorphism and control of SIV infection
por: Shiina, Takashi, et al.
Publicado: (2019)

Adipose Tissue Is a Neglected Viral Reservoir and an Inflammatory Site during Chronic HIV and SIV Infection
por: Damouche, Abderaouf, et al.
Publicado: (2015)

In-Depth Characterization of Full-Length Archived Viral Genomes after Nine Years of Posttreatment HIV Control
por: Trémeaux, Pauline, et al.
Publicado: (2023)

Dynamics in HIV‐DNA levels over time in HIV controllers
por: Avettand‐Fenoel, Véronique, et al.
Publicado: (2019)

Role of NKG2a/c(+)CD8(+) T cells in pathogenic versus non-pathogenic SIV infections
por: Huot, Nicolas, et al.
Publicado: (2021)

Loss and regain of SIV control upon CD8+ cell depletion in vivo in SIV-controller macaques is not associated with efficient SIV specific CD8+ T-cells
por: Hamimi, C, et al.
Publicado: (2012)

Post-Treatment HIV-1 Controllers with a Long-Term Virological Remission after the Interruption of Early Initiated Antiretroviral Therapy ANRS VISCONTI Study
por: Sáez-Cirión, Asier, et al.
Publicado: (2013)

Tissue viral dynamics in SIV infected macaques with highly active antiretroviral therapy (HAART)
por: Bourry, Olivier, et al.
Publicado: (2009)

Total HIV DNA: a global marker of HIV persistence
por: Rouzioux, Christine, et al.
Publicado: (2018)

Mass Cytometry Analysis Reveals the Landscape and Dynamics of CD32a(+) CD4(+) T Cells From Early HIV Infection to Effective cART
por: Coindre, Sixtine, et al.
Publicado: (2018)

Pro-viral DNA and antiretroviral treatment simplification
por: Zucman, D, et al.
Publicado: (2010)

Detection of SARS-CoV-2 in subcutaneous fat but not visceral fat, and the disruption of fat lymphocyte homeostasis in both fat tissues in the macaque
por: Olivo, Anaëlle, et al.
Publicado: (2022)

Neuroinflammatory Profiling in SIV-Infected Chinese-Origin Rhesus Macaques on Antiretroviral Therapy
por: Solis-Leal, Antonio, et al.
Publicado: (2022)

Antiretroviral therapy restores the homeostatic state of microglia in SIV‐infected rhesus macaques
por: Trease, Andrew J., et al.
Publicado: (2022)

Effects of therapeutic vaccination on the control of SIV in rhesus macaques with variable responsiveness to antiretroviral drugs
por: Tunggal, Hillary Claire, et al.
Publicado: (2021)

Butyrate administration is not sufficient to improve immune reconstitution in antiretroviral-treated SIV-infected macaques
por: Ortiz, Alexandra M., et al.
Publicado: (2022)

Clinical monitoring and correlates of nephropathy in SIV-infected macaques during high-dose antiretroviral therapy
por: Sanders-Beer, Brigitte E, et al.
Publicado: (2011)

Multi-dose Romidepsin Reactivates Replication Competent SIV in Post-antiretroviral Rhesus Macaque Controllers
por: Policicchio, Benjamin B., et al.
Publicado: (2016)

Interleukin-10 contributes to reservoir establishment and persistence in SIV-infected macaques treated with antiretroviral therapy
por: Harper, Justin, et al.
Publicado: (2022)

Blunted Response to Combination Antiretroviral Therapy in HIV Elite Controllers: An International HIV Controller Collaboration
por: Boufassa, Faroudy, et al.
Publicado: (2014)

Host Immunity to Mycobacterium tuberculosis Infection Is Similar in Simian Immunodeficiency Virus (SIV)-Infected, Antiretroviral Therapy-Treated and SIV-Naïve Juvenile Macaques
por: Larson, Erica C., et al.
Publicado: (2023)

NK cell spatial dynamics and IgA responses in gut-associated lymphoid tissues during SIV infections
por: Rascle, Philippe, et al.
Publicado: (2022)

The role of cytotoxic T cells
por: Sáez-Cirión, Asier
Publicado: (2010)

Plasmodium infection reduces the volume of the viral reservoir in SIV-infected rhesus macaques receiving antiretroviral therapy
por: Zhan, Xiao-Yong, et al.
Publicado: (2014)

Clonal expansion of SIV-infected cells in macaques on antiretroviral therapy is similar to that of HIV-infected cells in humans
por: Ferris, Andrea L., et al.
Publicado: (2019)

Alterations of the gut bacterial microbiota in rhesus macaques with SIV infection and on short- or long-term antiretroviral therapy
por: Siddiqui, Summer, et al.
Publicado: (2020)

SIV Evolutionary Dynamics in Cynomolgus Macaques during SIV-Mycobacterium tuberculosis Co-Infection
por: Tisthammer, Kaho H., et al.
Publicado: (2021)

Persistent Viral Reservoirs in Lymphoid Tissues in SIV-Infected Rhesus Macaques of Chinese-Origin on Suppressive Antiretroviral Therapy
por: Siddiqui, Summer, et al.
Publicado: (2019)

Liver Bacterial Dysbiosis With Non-Tuberculosis Mycobacteria Occurs in SIV-Infected Macaques and Persists During Antiretroviral Therapy
por: Fisher, Bridget S., et al.
Publicado: (2022)

Viral dissemination and immune activation modulate antiretroviral drug levels in lymph nodes of SIV-infected rhesus macaques
por: Srinivasula, Sharat, et al.
Publicado: (2023)

Cannot write session to /tmp/vufind_sessions/sess_b5isgf6bb79pumimo4gdu2cv76