Cargando…

Targeting the DNA Damage Response and DNA Repair Pathways to Enhance Radiosensitivity in Colorectal Cancer

SIMPLE SUMMARY: The DNA damage response pathway plays a critical role in maintaining genomic integrity. Therefore, inhibition of activation of cell-cycle checkpoints involved in this pathway may increase the sensitivity of tumor cells to DNA damage induced by ionizing radiation. In this review, we p...

Descripción completa

Detalles Bibliográficos
Autores principales: Deng, Siyao, Vlatkovic, Tijana, Li, Moying, Zhan, Tianzuo, Veldwijk, Marlon R., Herskind, Carsten
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9561988/
https://www.ncbi.nlm.nih.gov/pubmed/36230796
http://dx.doi.org/10.3390/cancers14194874