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Targeting the DNA Damage Response and DNA Repair Pathways to Enhance Radiosensitivity in Colorectal Cancer

SIMPLE SUMMARY: The DNA damage response pathway plays a critical role in maintaining genomic integrity. Therefore, inhibition of activation of cell-cycle checkpoints involved in this pathway may increase the sensitivity of tumor cells to DNA damage induced by ionizing radiation. In this review, we p...

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Detalles Bibliográficos
Autores principales:	Deng, Siyao, Vlatkovic, Tijana, Li, Moying, Zhan, Tianzuo, Veldwijk, Marlon R., Herskind, Carsten
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2022
Materias:	Review
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9561988/ https://www.ncbi.nlm.nih.gov/pubmed/36230796 http://dx.doi.org/10.3390/cancers14194874

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