Breast Tumor Cell-Stimulated Bone Marrow-Derived Mesenchymal Stem Cells Promote the Sprouting Capacity of Endothelial Cells by Promoting VEGF Expression, Mediated in Part through HIF-1α Increase

SIMPLE SUMMARY: ROS and JAK/Stat3 cooperatively upregulate the expression of HIF-1α in bone marrow-derived mesenchymal stem cells under normoxic conditions in response to breast tumor cells. The upregulation of HIF-1α contributes in part to the increase in VEGF expression in the bone marrow-derived...

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Detalles Bibliográficos
Autores principales: Kim, Wootak, Park, Aran, Jang, Hyun Hee, Kim, Seung-Eun, Park, Ki-Sook
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9562024/
https://www.ncbi.nlm.nih.gov/pubmed/36230633
http://dx.doi.org/10.3390/cancers14194711

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9562024/
https://www.ncbi.nlm.nih.gov/pubmed/36230633
http://dx.doi.org/10.3390/cancers14194711

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