Cargando…

Breast Tumor Cell-Stimulated Bone Marrow-Derived Mesenchymal Stem Cells Promote the Sprouting Capacity of Endothelial Cells by Promoting VEGF Expression, Mediated in Part through HIF-1α Increase

SIMPLE SUMMARY: ROS and JAK/Stat3 cooperatively upregulate the expression of HIF-1α in bone marrow-derived mesenchymal stem cells under normoxic conditions in response to breast tumor cells. The upregulation of HIF-1α contributes in part to the increase in VEGF expression in the bone marrow-derived...

Descripción completa

Detalles Bibliográficos
Autores principales:	Kim, Wootak, Park, Aran, Jang, Hyun Hee, Kim, Seung-Eun, Park, Ki-Sook
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2022
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9562024/ https://www.ncbi.nlm.nih.gov/pubmed/36230633 http://dx.doi.org/10.3390/cancers14194711

Ejemplares similares

Bone Marrow-Derived Mesenchymal Stem Cells Migrate toward Hormone-Insensitive Prostate Tumor Cells Expressing TGF-β via N-Cadherin
por: Noh, Jinok, et al.
Publicado: (2021)

N-cadherin mediates the migration of bone marrow-derived mesenchymal stem cells toward breast tumor cells
por: Choi, Sanghyuk, et al.
Publicado: (2021)

Bone Marrow-Derived Vasculogenic Mesenchymal Stem Cells Enhance In Vitro Angiogenic Sprouting of Human Umbilical Vein Endothelial Cells
por: Jang, Hyun Hee, et al.
Publicado: (2022)

Coordinated Regulation of Mesenchymal Stem Cell Migration by Various Chemotactic Stimuli
por: Nam, Donghyun, et al.
Publicado: (2020)

VEGF guides angiogenic sprouting utilizing endothelial tip cell filopodia
por: Gerhardt, Holger, et al.
Publicado: (2003)

AKAP12 deficiency impairs VEGF‐induced endothelial cell migration and sprouting
por: Benz, Peter M., et al.
Publicado: (2019)

ADAM17 Promotes Motility, Invasion, and Sprouting of Lymphatic Endothelial Cells
por: Mężyk-Kopeć, Renata, et al.
Publicado: (2015)

Endothelial Insulin Receptors Promote VEGF-A Signaling via ERK1/2 and Sprouting Angiogenesis
por: Walker, Andrew M N, et al.
Publicado: (2021)

VEGF treatment promotes bone marrow-derived CXCR4(+) mesenchymal stromal stem cell differentiation into vessel endothelial cells
por: Li, Qiming, et al.
Publicado: (2017)

Pericytes regulate VEGF-induced endothelial sprouting through VEGFR1
por: Eilken, Hanna M., et al.
Publicado: (2017)

Endothelial Semaphorin 3fb regulates Vegf pathway-mediated angiogenic sprouting
por: Watterston, Charlene, et al.
Publicado: (2021)

Transcriptional regulation of endothelial cell behavior during sprouting angiogenesis
por: Jeong, Hyun-Woo, et al.
Publicado: (2017)

Syntenin promotes VEGF-induced VEGFR2 endocytosis and angiogenesis by increasing ephrin-B2 function in endothelial cells
por: Tae, Nara, et al.
Publicado: (2017)

Inhibitor of differentiation 1 in U87MG glioblastoma cells promotes HUVEC sprouting through endothelin-1
por: Choi, Sang-Hun, et al.
Publicado: (2022)

Ges, a Human Gtpase of the Rad/Gem/Kir Family, Promotes Endothelial Cell Sprouting and Cytoskeleton Reorganization
por: Pan, Julie Y., et al.
Publicado: (2000)

Cationic Nanocylinders Promote Angiogenic Activities of Endothelial Cells
por: Lee, Jung Bok, et al.
Publicado: (2016)

Clinicopathologic significance of HIF-1α, p53, and VEGF expression and preoperative serum VEGF level in gastric cancer
por: Oh, Sung Yong, et al.
Publicado: (2008)

HIF-2α Expression Regulates Sprout Formation into 3D Fibrin Matrices in Prolonged Hypoxia in Human Microvascular Endothelial Cells
por: Nauta, Tessa D., et al.
Publicado: (2016)

Melatonin restricts the viability and angiogenesis of vascular endothelial cells by suppressing HIF-1α/ROS/VEGF
por: Cheng, Jiao, et al.
Publicado: (2019)

Retraction: Rapamycin Inhibits Proliferation of Hemangioma Endothelial Cells by Reducing HIF-1-Dependent Expression of VEGF
Publicado: (2020)

Development of a 3-D Physical Dynamics Monitoring System Using OCM with DVC for Quantification of Sprouting Endothelial Cells Interacting with a Collagen Matrix
por: Kang, Yong Guk, et al.
Publicado: (2020)

VEGF promotes endothelial progenitor cell differentiation and vascular repair through connexin 43
por: Li, Lufeng, et al.
Publicado: (2017)

Fructose promotes angiogenesis by improving vascular endothelial cell function and upregulating VEGF expression in cancer cells
por: Cui, Yanfen, et al.
Publicado: (2023)

MAPK/ERK signalling mediates VEGF-induced bone marrow stem cell differentiation into endothelial cell
por: Xu, J, et al.
Publicado: (2008)

Endothelial cell division in angiogenic sprouts of differing cellular architecture
por: Aydogan, Vahap, et al.
Publicado: (2015)

Modelling of chemotactic sprouting endothelial cells through an extracellular matrix
por: Ferre-Torres, Josep, et al.
Publicado: (2023)

Correction: HIF-2α Expression Regulates Sprout Formation into 3D Fibrin Matrices in Prolonged Hypoxia in Human Microvascular Endothelial Cells
por: Nauta, Tessa D., et al.
Publicado: (2016)

Role of Mir-155 in Controlling HIF-1α Level and Promoting Endothelial Cell Maturation
por: Yang, Deguang, et al.
Publicado: (2016)

DNA topoisomerase inhibition with the HIF inhibitor acriflavine promotes transcription of lncRNAs in endothelial cells
por: Seredinski, Sandra, et al.
Publicado: (2022)

Hyperthermia Influences the Secretion Signature of Tumor Cells and Affects Endothelial Cell Sprouting
por: Maduabuchi, Wisdom O., et al.
Publicado: (2023)

Hypoxic Regulation of VEGF, HIF-1(alpha) in Coronary Collaterals Development
por: Sung, Ki Chul, et al.
Publicado: (2005)

KLF4 Promotes Angiogenesis by Activating VEGF Signaling in Human Retinal Microvascular Endothelial Cells
por: Wang, Yinan, et al.
Publicado: (2015)

Bone marrow endothelial dysfunction promotes myeloid cell expansion in cardiovascular disease
por: Rohde, David, et al.
Publicado: (2022)

Overexpressed Neuropilin-1 in Endothelial Cells Promotes Endothelial Permeability through Interaction with ANGPTL4 and VEGF in Kawasaki Disease
por: Huang, Junhua, et al.
Publicado: (2021)

Endothelial Cell mTOR Complex-2 Regulates Sprouting Angiogenesis
por: Farhan, Maikel A., et al.
Publicado: (2015)

Control of endothelial cell polarity and sprouting angiogenesis by non-centrosomal microtubules
por: Martin, Maud, et al.
Publicado: (2018)

Dynamic Interplay between Pericytes and Endothelial Cells during Sprouting Angiogenesis
por: Chiaverina, Giulia, et al.
Publicado: (2019)

Effects of bevacizumab on the neovascular membrane of proliferative diabetic retinopathy: reduction of endothelial cells and expressions of VEGF and HIF-1α
por: Han, Xiao-Xia, et al.
Publicado: (2012)

Peroxiredoxin 1 Stimulates Endothelial Cell Expression of VEGF via TLR4 Dependent Activation of HIF-1α
por: Riddell, Jonah R., et al.
Publicado: (2012)

Effect of the Recombinant Adenovirus-Mediated HIF-1 Alpha on the Expression of VEGF in the Hypoxic Brain Microvascular Endothelial Cells of Rats
por: Jin, Ming-Lu, et al.
Publicado: (2020)

Cannot write session to /tmp/vufind_sessions/sess_ua2ne4rjqt2mdojohr0nbhekfo