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APRIL/BLyS deficient rats prevent donor specific antibody (DSA) production and cell proliferation in rodent kidney transplant model

APRIL (A proliferation inducing ligand) and BLyS (B Lymphocyte Stimulator) are two critical survival factors for B lymphocytes and plasma cells, the main source of alloantibody. We sought to characterize the specific effects of these cytokines in a kidney transplant model of antibody mediated reject...

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Detalles Bibliográficos
Autores principales: Bath, Natalie M., Verhoven, Bret M., Wilson, Nancy A., Zeng, Weifeng, Zhong, Weixiong, Coons, Lauren, Djamali, Arjang, Redfield, Robert R.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9562156/
https://www.ncbi.nlm.nih.gov/pubmed/36227902
http://dx.doi.org/10.1371/journal.pone.0275564