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CREPT Disarms the Inhibitory Activity of HDAC1 on Oncogene Expression to Promote Tumorigenesis
SIMPLE SUMMARY: It has been proposed that highly expressed HDAC1 (histone deacetylases 1) removes the acetyl group from the histones at the promoter regions of tumor suppressor genes to block their expression in tumors. We here revealed the underlying mechanism that HDAC1 differentially regulates th...
Autores principales: | Cao, Yajun, Ning, Bobin, Tian, Ye, Lan, Tingwei, Chu, Yunxiang, Ren, Fangli, Wang, Yinyin, Meng, Qingyu, Li, Jun, Jia, Baoqing, Chang, Zhijie |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9562184/ https://www.ncbi.nlm.nih.gov/pubmed/36230720 http://dx.doi.org/10.3390/cancers14194797 |
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