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CREPT Disarms the Inhibitory Activity of HDAC1 on Oncogene Expression to Promote Tumorigenesis

SIMPLE SUMMARY: It has been proposed that highly expressed HDAC1 (histone deacetylases 1) removes the acetyl group from the histones at the promoter regions of tumor suppressor genes to block their expression in tumors. We here revealed the underlying mechanism that HDAC1 differentially regulates th...

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Detalles Bibliográficos
Autores principales: Cao, Yajun, Ning, Bobin, Tian, Ye, Lan, Tingwei, Chu, Yunxiang, Ren, Fangli, Wang, Yinyin, Meng, Qingyu, Li, Jun, Jia, Baoqing, Chang, Zhijie
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9562184/
https://www.ncbi.nlm.nih.gov/pubmed/36230720
http://dx.doi.org/10.3390/cancers14194797

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