Does Dapagliflozin influence arterial stiffness and levels of circulating anti-aging hormone soluble Klotho in people with type 2 diabetes and kidney disease? Results of a randomized parallel group clinical trial

OBJECTIVE: The mechanisms that explain the cardio-renal benefits of sodium glucose co-transporter 2 (SGLT-2) inhibitors are unknown. The effect of SGLT-2 inhibitors on arterial aging, measured by Aortic Pulse Wave Velocity (Ao-PWV) and Soluble Klotho (s-Klotho), a circulating anti-aging biomarker of...

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Detalles Bibliográficos
Autores principales: Karalliedde, Janaka, Fountoulakis, Nikos, Stathi, Dimitra, Corcillo, Antonella, Flaquer, Maria, Panagiotou, Angeliki, Maltese, Giuseppe, Mangelis, Anastasios, Ayis, Salma, Gnudi, Luigi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Cardiovascular Medicine
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9562264/
https://www.ncbi.nlm.nih.gov/pubmed/36247425
http://dx.doi.org/10.3389/fcvm.2022.992327

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9562264/
https://www.ncbi.nlm.nih.gov/pubmed/36247425
http://dx.doi.org/10.3389/fcvm.2022.992327

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