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Does Dapagliflozin influence arterial stiffness and levels of circulating anti-aging hormone soluble Klotho in people with type 2 diabetes and kidney disease? Results of a randomized parallel group clinical trial

OBJECTIVE: The mechanisms that explain the cardio-renal benefits of sodium glucose co-transporter 2 (SGLT-2) inhibitors are unknown. The effect of SGLT-2 inhibitors on arterial aging, measured by Aortic Pulse Wave Velocity (Ao-PWV) and Soluble Klotho (s-Klotho), a circulating anti-aging biomarker of...

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Detalles Bibliográficos
Autores principales:	Karalliedde, Janaka, Fountoulakis, Nikos, Stathi, Dimitra, Corcillo, Antonella, Flaquer, Maria, Panagiotou, Angeliki, Maltese, Giuseppe, Mangelis, Anastasios, Ayis, Salma, Gnudi, Luigi
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Frontiers Media S.A. 2022
Materias:	Cardiovascular Medicine
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9562264/ https://www.ncbi.nlm.nih.gov/pubmed/36247425 http://dx.doi.org/10.3389/fcvm.2022.992327

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