Reaction of Thiosulfate Dehydrogenase with a Substrate Mimic Induces Dissociation of the Cysteine Heme Ligand Giving Insights into the Mechanism of Oxidative Catalysis

[Image: see text] Thiosulfate dehydrogenases are bacterial cytochromes that contribute to the oxidation of inorganic sulfur. The active sites of these enzymes contain low-spin c-type heme with Cys(–)/His axial ligation. However, the reduction potentials of these hemes are several hundred mV more neg...

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Detalles Bibliográficos
Autores principales: Jenner, Leon P., Crack, Jason C., Kurth, Julia M., Soldánová, Zuzana, Brandt, Linda, Sokol, Katarzyna P., Reisner, Erwin, Bradley, Justin M., Dahl, Christiane, Cheesman, Myles R., Butt, Julea N.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Chemical Society 2022
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9562282/
https://www.ncbi.nlm.nih.gov/pubmed/36173876
http://dx.doi.org/10.1021/jacs.2c06062

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