The Hippo pathway links adipocyte plasticity to adipose tissue fibrosis

Fibrosis disrupts adipose tissue (AT) homeostasis and exacerbates metabolic dysfunction upon chronic caloric excess. The molecular mechanisms linking adipocyte plasticity to AT fibrosis are largely unknown. Here we show that the Hippo pathway is coupled with TGFβ signaling to orchestrate a cellular...

Descripción completa

Detalles Bibliográficos
Autores principales: Shen, Hongyu, Huang, Xun, Zhao, Yiheng, Wu, Dongmei, Xue, Kaili, Yao, Jingfei, Wang, Yushuang, Tang, Nan, Qiu, Yifu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9562301/
https://www.ncbi.nlm.nih.gov/pubmed/36229481
http://dx.doi.org/10.1038/s41467-022-33800-0

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9562301/
https://www.ncbi.nlm.nih.gov/pubmed/36229481
http://dx.doi.org/10.1038/s41467-022-33800-0

Ejemplares similares