Structural and functional analysis of EntV reveals a 12 amino acid fragment protective against fungal infections

Fungal pathogens are a continuing challenge due to few effective antifungals and a rise in resistance. In previous work, we described the inhibition of Candida albicans virulence following exposure to the 68 amino acid bacteriocin, EntV, secreted by Enterococcus faecalis. Here, to optimize EntV as a...

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Detalles Bibliográficos
Autores principales: Cruz, Melissa R., Cristy, Shane, Guha, Shantanu, De Cesare, Giuseppe Buda, Evdokimova, Elena, Sanchez, Hiram, Borek, Dominika, Miramón, Pedro, Yano, Junko, Fidel, Paul L., Savchenko, Alexei, Andes, David R., Stogios, Peter J., Lorenz, Michael C., Garsin, Danielle A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9562342/
https://www.ncbi.nlm.nih.gov/pubmed/36229448
http://dx.doi.org/10.1038/s41467-022-33613-1

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