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Overexpression of mouse prion protein in transgenic mice causes a non-transmissible spongiform encephalopathy

Transgenic mice over-expressing human PRNP or murine Prnp transgenes on a mouse prion protein knockout background have made key contributions to the understanding of human prion diseases and have provided the basis for many of the fundamental advances in prion biology, including the first report of...

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Detalles Bibliográficos
Autores principales:	Jackson, Graham S., Linehan, Jacqueline, Brandner, Sebastian, Asante, Emmanuel A., Wadsworth, Jonathan D. F., Collinge, John
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group UK 2022
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9562354/ https://www.ncbi.nlm.nih.gov/pubmed/36229637 http://dx.doi.org/10.1038/s41598-022-21608-3

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