Genetic deconvolution of fetal and maternal cell-free DNA in maternal plasma enables next-generation non-invasive prenatal screening

Current non-invasive prenatal screening (NIPS) analyzes circulating fetal cell-free DNA (cfDNA) in maternal peripheral blood for selected aneuploidies or microdeletion/duplication syndromes. Many genetic disorders are refractory to NIPS largely because the maternal genetic material constitutes most...

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Detalles Bibliográficos
Autores principales: Xu, Chenming, Li, Jianli, Chen, Songchang, Cai, Xiaoqiang, Jing, Ruilin, Qin, Xiaomei, Pan, Dong, Zhao, Xin, Ma, Dongyang, Xu, Xiufeng, Liu, Xiaojun, Wang, Can, Yang, Bingxin, Zhang, Lanlan, Li, Shuyuan, Chen, Yiyao, Pan, Nina, Tang, Ping, Song, Jieping, Liu, Nian, Zhang, Chen, Zhang, Zhiwei, Qiu, Xiang, Lu, Weiliang, Ying, Chunmei, Li, Xiaotian, Xu, Congjian, Wang, Yanlin, Wu, Yanting, Huang, He-Feng, Zhang, Jinglan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer Nature Singapore 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9562363/
https://www.ncbi.nlm.nih.gov/pubmed/36229437
http://dx.doi.org/10.1038/s41421-022-00457-4

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