Anti-ANGPTL3-FLD monoclonal antibody treatment ameliorates podocyte lesions through attenuating mitochondrial damage

Proteinuria, an indication of kidney disease, is caused by the malfunction of podocytes, which play a key role in maintaining glomerular filtration. Angiopoietin-like 3 (ANGPTL3) has been documented to have a cell-autonomous involvement in podocytes, and deletion of Angptl3 in podocytes reduced prot...

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Detalles Bibliográficos
Autores principales: Lv, Qianying, Han, Xinli, Ni, Jiajia, Ma, Qianqian, Dai, Rufeng, Liu, Jiaojiao, Liu, Jialu, Zhai, Yihui, Shen, Qian, Sun, Li, Liu, Haimei, Rao, Jia, Xu, Hong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9562403/
https://www.ncbi.nlm.nih.gov/pubmed/36229446
http://dx.doi.org/10.1038/s41419-022-05313-7

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